![]() ![]() ![]() Food and Drug Administration (FDA) approval in 1936. Black widow spider antivenin (Merck & Co., Inc.) (Merck BW-AV) has been available in the United States since its U.S. 12 Currently, one commercially available Latrodectus antivenom exists in the United States. Although commercially available antivenom exists in the United States for treatment of Loxosceles envenomation, antivenom produced for South American Loxosceles spiders demonstrates cross-reactivity with North American species like L. geometricus was introduced) and Loxosceles. Of the species of spiders of medical importance in the United States, two of the most notable are Latrodectus ( L.
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